Addiction is defined as a substance or behaviour who acts as a part to study the alcohol and other drugs which leads to such behaviours. The Immune system of the body and also the nervous system plays a major part in the addiction process. The maximum addiction behaviour can be seen when the person is in serious stressful conditions. The Innate immunity consist of some genes which are inducted when some cells of the nervous system and immune system are activated with the help of environmental factors and also stress factors. These two types of factors can be observed in an alcohol addicted person only. The nuclear protein “factor-κB” activates the immune system genes which are involved in gene induction process. The frontal cortex was one of the areas in the central brain where the gene induction takes place which directly leads to addiction. The addictive behaviour will be more in an individual if the variability of the genotypes increases which results in sensory adaptation. The addictive drinking behaviour can be controlled with the alterations in the neuro immune genes which linked to the alcohol effect. The resulting information will increase our knowledge on drug addiction and help in the development of new therapies & theories which helps in the treatment for addiction.
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